Cushing syndrome, also referred to as hypercortisolism, is a disorder that occurs when too much cortisol is produced in the body over a long period of time. It can happen for a variety of reasons though some of the most common causes are typically the use of oral corticosteroid medication or when your body simply makes too much cortisol itself [1].

See also: Stressed out? The Dangers of High Cortisol and Stress

Cushing syndrome symptoms

The signs and symptoms of Cushing syndrome can vary depending on the person as well as how high the levels of cortisol actually are [2]. With that in mind, there are some common indicators to be aware of, these include:

  • Weight gain
  • Fragile skin
  • A ‘buffalo hump’ between the shoulders
  • Slow healing of cuts, bites or infections
  • Acne
  • Severe fatigue
  • Muscle weakness

Cushing syndrome causes

Two of the most common causes of Cushing syndrome are the long-term use of oral corticosteroid medication and your body's own overproduction of the hormone - this overproduction typically occurs as a result of certain types of tumors, these include [3]:

  • Pituitary gland tumor
  • ACTH-secreting tumor
  • Adrenal tumors

If you are experiencing signs or symptoms of Cushing syndrome, it’s important to know more. This can be done by taking a trip to the doctor or from home with an at-home lab test.

LetsGetChecked’s at-home Cortisol Test can measure adrenal performance or stress with online results available within 2-5 days and access to our medical experts every step of the way.

You should consider taking the test if:

  • You constantly feel run down
  • You are body-building competitively
  • You are presenting with symptoms of Cushing syndrome
  • You have Cushing syndrome
  • You are presenting with symptoms of Addison's disease
  • You have Addison's disease
  • You take or have been taking testosterone

See also: How do you Check Cortisol Levels From Home?


  1. Mayo Clinic. Cushing Syndrome. Online:, 2019
  2. Mayo Clinic. Cushing Syndrome. Online:, 2019
  3. National Institute of Diabetes and Digestive and Kidney Disease. Cushing’s Syndrome. Online:, 2018