Thyroid Peroxidase Antibodies (TPO/TPEX) Test

$119 $119

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At home thyroid peroxidase antibodies (TPO/TPEX) test. Part of our thyroid antibody test will provide a complete picture of how your thyroid is performing, with online results in 2 to 5 days.

What does it test for?

  • Thyroid Peroxidase Antibodies (TPO/TPEX)
  • Thyroid Stimulating Hormone (TSH)
  • Free Thyroxine (FT4)
  • Free Triiodothyronine (FT3)
  • Thyroglobulin Antibodies (TGAB)

Collection method


Purchase options
$119 $119
This test is not permitted for use in NY due to state restrictions.

FSA & HSA cards accepted.

This test is not permitted for use in NY due to state restrictions.

FSA & HSA cards accepted.

Hypothyroidism (Underactive Thyroid) occurs when the thyroid gland is not producing a sufficient level of thyroxine (T4) and triiodothyronine (T3).

  • Weight gain
  • Fatigue or feeling tired all the time
  • Slow pulse or heart rate
  • Hair loss or thinning
  • Poor tolerance of the cold
  • Depression
  • Dry, coarse or thickened skin
  • Constipation
  • Hand tingling or pain (carpal tunnel syndrome)
  • Irregular period or low sex drive
  • Muscle cramps
  • Impaired memory

Hyperthyroidism (Overactive Thyroid) occurs when the thyroid gland produces an excessive level of thyroxine (T4) and triiodothyronine (T3).

  • Weight loss
  • Fatigue or feeling tired all the time
  • Increase or rapid heart rate
  • Tremors (usually in the hands)
  • Heat intolerance or excessive sweating
  • Difficulty sleeping
  • Excessive sweating or fever
  • Frequent colon movements or diarrhea
  • Anxiety
  • Irregular period
  • Low sex drive
  • Enlarged thyroid gland (goiter)
  • Eye condition related to hyperthyroidism

You should consider getting tested if you:

  • Have symptoms of an overactive thyroid
  • Have symptoms of an underactive thyroid
  • Have a family history of thyroid conditions
  • Have an autoimmune condition such as celiac disease or type 1 diabetes
  • Thyroid Stimulating Hormone (TSH)

    Thyroid stimulating hormone (TSH), also known as thyrotropin, is a hormone produced by the pituitary gland of the brain. The release of TSH stimulates the thyroid gland to produce thyroxine (T4) and triiodothyronine (T3). These hormones regulate the body’s metabolism.

  • Free Thyroxine (FT4)

    Free thyroxine (FT4) is the biologically active form of thyroxine, a hormone produced in the thyroid gland to regulate your metabolism. FT4 is not bound to proteins and is available for use by the tissues of the body. Raised FT4 levels can indicate an overactive thyroid (hyperthyroidism), low FT4 levels can indicate an under active thyroid (hypothyroidism).

  • Free Triiodothyronine (FT3)

    Free triiodothyronine (FT3) is one of two major hormones produced by the thyroid gland. FT3 is more biologically active than thyroxine (T4) and is required to regulate metabolism. FT3 is produced directly by the thyroid gland, and through the conversion of T4 to T3 in other cells of the body.

  • Thyroglobulin Antibodies (TGAB)

    TGAB is an antibody which can indicate thyroid damage caused by an autoimmune disorder.

  • Thyroid Peroxidase Antibodies (TPO/TPEX)

    TPEX is an antibody which can indicate thyroid damage caused by an autoimmune disorder.



How to collect your sample

Watch our instructional video to see how easy it is to collect your sample.


How it works

Person opening test kit

Collect Your Sample

Activate your test and collect your sample in the morning. Return your sample on the same day, using the prepaid shipping label provided.

Person opening test kit

Review Accurate Results

Once your sample arrives in the laboratory, confidential results will be available from your secure online account within 2 to 5 days.

Person reviewing results on a phone

Get Medical Support

Our dedicated team of nurses are available 24/7 and will call you to explain your results.


Still have questions?

Here are some questions we usually get about LetsGetChecked. If you would like yours answered, please contact us.

The home thyroid antibody test is for anyone who has symptoms of hyperthyroidism, hypothyroidism, has a family history of thyroid disease, has an autoimmune disorder or takes performance enhancing substances.

Activating the test connects you to the unique alphanumeric barcode within your LetsGetChecked sample collection kit. The laboratory cannot process your sample if the test is not activated and linked to you. You should only activate your test when you are ready to take your sample.

Yes. LetsGetChecked has a team of board-certified physicians who will review your order and results and have created detailed result breakdowns for your testing journey.

Our nursing team is on standby throughout the testing process and, if your test results are abnormal, you will receive a call to discuss your results and next steps.

Please ensure that the sample is collected before 9am and returned immediately using the carrier method provided within the sample collection kit. It is not usually necessary to fast for this test, although sometimes not fasting can have a small impact on TSH levels. Talk to your healthcare provider about what is best for you. Each of our health tests includes a prepaid shipping envelope to return your samples to the laboratory.

Please do not collect or return samples on a Friday, Saturday or Sunday.

Keeping your personal data secure is important to us. We use appropriate technical and organizational measures to ensure security and confidentiality of your information, and only share your information where required to deliver our products and services or where we have a legal basis to do so. All samples are disposed of following analysis.

Your samples are processed in the same labs used by primary care providers, hospitals and government programs.

LetsGetChecked laboratories are CLIA approved and CAP-accredited, which are the highest levels of accreditation.

Sample collection kits are manufactured within our ISO 13485 accredited facility, the highest level of accreditation for medical devices.

We don't accept insurance at this time. We work to keep our tests as affordable as possible and our test costs are generally lower than the costs incurred from a trip to a healthcare provider.

We accept many Flexible Spending Accounts (FSA) and Health Savings Accounts (HSA) cards. They can be used in the same way that a debit or credit card would be used at checkout.

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